In addition, you can select in between the KVM Switches price ranges, KVM Switches brand names, or KVM Switches specs that you VS0.8-1.0Vp-p/75Ω

av M Merza · 2015 · Citerat av 139 — P-selectin mediates neutrophil rolling and recruitment in acute pancreatitis. Br J Surg. 2012; 99: 246-255. View in Article. Scopus (44) · PubMed

Meaning of p-selectin. What does p-selectin mean? Information and translations of p-selectin in the most comprehensive dictionary definitions resource on the web. P-selectin is a cell adhesion molecule of platelets and endothelial cells stored in secretory granules and rapidly expressed on the plasma membrane on activation.10-13 After expression on the cell surface both endothelial and platelet P-selectin mediate leukocyte adhesion.14 Whereas endothelial P-selectin has clearly been shown to be involved This tight link is partly attributable to P-selectin, which is functional not only when expressed on the surface of activated platelets and endothelial cells, but also when shed, generating its soluble form, termed sP-selectin. P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets.

Select . in Hift . Svecan , P. V , p . In addition, you can select in between the KVM Switches price ranges, KVM Switches brand names, or KVM Switches specs that you VS0.8-1.0Vp-p/75Ω P-selectin is a type-1 transmembrane protein that in humans is encoded by the SELP gene.. P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets.

P-selectin can be secreted into the circulation as a component of EC and platelet-derived microparticles (MP) or, in small quantities, as a free, alternatively spliced version lacking a transmembrane domain. 25 These two forms of soluble P-selectin are elevated in humans in association with atherosclerosis and thrombosis and are predictive of future adverse cardiovascular events, including The adhesion molecule P-selectin (CD62P) is of interest because of its role in modulating interactions between blood cells and the endothelium, and also because of the possible use of the soluble form as a plasma predictor of adverse cardiovascular events.

Inkluderar: P-Selectin, p-selectin — Visa detaljer. Taggade verk. Oftast taggat | Viktat | Populärt just nu | Nypublicerat — Filter: Ingen/inga (ändra). Använder

Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells. 2011-08-17 · P-selectin expression is involved in the pathophysiology of biologically active arterial thrombus and endothelial activation after a transient ischemic event. Fucoidan is a polysaccharidic ligand of P-selectin, with a nanomolar affinity. In the present study, we propose a new approach of P-selectin molecular imaging based on radiolabeled fucoidan.

Definition of p-selectin in the Definitions.net dictionary. Meaning of p-selectin. What does p-selectin mean? Information and translations of p-selectin in the most comprehensive dictionary definitions resource on the web.

Although present on the external cell surfa … P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex ) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-selectin is a cell adhesion molecule of platelets and endothelial cells stored in secretory granules and rapidly expressed on the plasma membrane on activation.10-13 After expression on the cell surface both endothelial and platelet P-selectin mediate leukocyte adhesion.14 Whereas endothelial P-selectin has clearly been shown to be involved in leukocyte and platelet rolling,15,16 the role of P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. P-selectin, L-selectin, and alpha 4 integrin have distinct roles in eosinophil tethering and arrest on vascular endothelial cells under physiological flow conditions J Immunol .

Konjugation, Unconjugated. Värd, Mouse. Isotyp, IgG1. ImmunoChemistry, Yes. By enzyme-linked immunosorbent assay, platelet surface expression of P-selectin was measured to estimate the state of activation on adherence.
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It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex ) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, P-selectin, the largest selectin, is stored in α-granules of platelets and in Weibel–Palade bodies of endothelial cells, and is translocated to the cell surface of activated endothelial cells and platelets. E-selectin is not expressed under baseline conditions, except in skin microvessels, but is rapidly induced by inflammatory cytokines. This tight link is partly attributable to P-selectin, which is functional not only when expressed on the surface of activated platelets and endothelial cells, but also when shed, generating its soluble form, termed sP-selectin. P-Selectin P-selektin Engelsk definition.
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P-Selectin Antibody (AK4) is a monoclonal anti-CD62 antibody that detects human P-Selectin by WB, IP, IF and FCM. Cited in 9 publications.

Meaning of p-selectin. What does p-selectin mean? Information and translations of p-selectin in the most comprehensive dictionary definitions resource on the web.

The R-PLEX platform offers matched sets of antibodies and calibrators for a wide menu of biomarkers. The R-PLEX Human P-Selectin Antibody Set can be used with other MSD components (see "Recommended Components" tab below) to build assays that measure P-Selectin.

We examined the role of P-selectin in the autologous phase of an Purpose. Vascular endothelial cells and leukocytes express several inflammatory adhesion receptors, such as selectins and cell adhesion molecules, after PE anti-human CD62P (P-Selectin) Antibody - CD62P is a 140 kD type I transmembrane glycoprotein also known as P-selectin, platelet activation- dependent Oct 4, 2017 Selectins are carbohydrate-binding proteins that are physiologically expressed on the surface of endothelial cells (P-selectin and E-selectin), The adhesion molecule P-selectin (CD62P) is of interest because of its role in modulating interactions between blood cells and the endothelium, and also Crystal structure of P-selectin lectin/EGF domains complexed with SLeX 1 Introduction; 2 3D structure; 3 Different roles of P-selectin. 3.1 Role in leukocyte Mar 15, 1998 Basically, ligands for L-selectin are found on endothelial cells while ligands for E- and P-selectins are found on leukocytes. Every selectin has Jan 4, 2013 diapedesis, selectin family of adhesion molecules, E-selectin, P-selectin, and chemotaxis are all explained. Kumar, Vinay, Abul K. Abbas, Dec 14, 2014 In this video we discuss the three different types of selectins and their P- Selectin and Pulmonary Arterial Thrombosis in Trauma and Disease P-Selektin.

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